Identification of N -(5- tert -Butyl-isoxazol-3-yl)- N ′-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1- b ][1,3]benzothiazol-2-yl]phenyl}urea Dihydrochloride (AC220), a Uniquely Potent, Selective, and Efficacious FMS-Like Tyrosine Kinase-3 (FLT3) Inhibitor

✍ Scribed by Chao, Qi; Sprankle, Kelly G.; Grotzfeld, Robert M.; Lai, Andiliy G.; Carter, Todd A.; Velasco, Anne Marie; Gunawardane, Ruwanthi N.; Cramer, Merryl D.; Gardner, Michael F.; James, Joyce; Zarrinkar, Patrick P.; Patel, Hitesh K.; Bhagwat, Shripad S.

• Book ID: 119994497
• Publisher: American Chemical Society
• Year: 2009
• Tongue: English
• Weight: 1000 KB
• Volume: 52
• Category: Article
• ISSN: 0022-2623
• DOI: 10.1021/jm9007533