Identification of N -(4-Piperidinyl)-4-(2,6-dichlorobenzoylamino)-1 H -pyrazole-3-carboxamide (AT7519), a Novel Cyclin Dependent Kinase Inhibitor Using Fragment-Based X-Ray Crystallography and Structure Based Drug Design †

✍ Scribed by Wyatt, Paul G.; Woodhead, Andrew J.; Berdini, Valerio; Boulstridge, John A.; Carr, Maria G.; Cross, David M.; Davis, Deborah J.; Devine, Lindsay A.; Early, Theresa R.; Feltell, Ruth E.; Lewis, E. Jonathan; McMenamin, Rachel L.; Navarro, Eva F.; O’Brien, Michael A.; O’Reilly, Marc; Reule, Matthias; Saxty, Gordon; Seavers, Lisa C. A.; Smith, Donna-Michelle; Squires, Matt S.; Trewartha, Gary; Walker, Margaret T.; Woolford, Alison J.-A.

• Book ID: 118238859
• Publisher: American Chemical Society
• Year: 2008
• Tongue: English
• Weight: 712 KB
• Volume: 51
• Category: Article
• ISSN: 0022-2623
• DOI: 10.1021/jm800382h