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Identification of model peptides as affinity ligands for the purification of humanized monoclonal antibodies by means of phage display

โœ Scribed by G.K Ehrlich; P Bailon


Book ID
117331144
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
213 KB
Volume
49
Category
Article
ISSN
0165-022X

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Identification of peptides that bind to
โœ George K. Ehrlich; Pascal Bailon ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 98 KB ๐Ÿ‘ 2 views

The pFc' fragments of a humanized IgG 1 monoclonal antibody were generated by digestion with immobilized pepsin. These pFc' fragments were separated from F(ab') 2 fragments by affinity chromatography. The pFc' fragments corresponding to the constant region of the humanized IgG 1 monoclonal antibody