Identification of MARCKS, FLJ11383 and TAF1B as putative novel target genes in colorectal carcinomas with microsatellite instability

Identification of novel genes with somat

Identification of novel genes with somatic frameshift mutations within coding mononucleotide repeats in colorectal tumors with high microsatellite instability

✍ Uroš Potočnik; Damjan Glavač; Metka Ravnik-Glavač 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 671 KB

## Abstract We have systematically retrieved genes with coding mononucleotide repeats from sequence databases and analyzed them for mutations in tumors with high levels of microsatellite instability (MSI‐H). We found somatic frameshift mutations in 7/13 genes previously not analyzed in MSI‐H tumors