## Abstract ## Objective The mechanisms by which chondrocytes convert biomechanical signals into intracellular biochemical events are not well understood. In this study, we sought to determine the intracellular mechanisms of the magnitude‐dependent actions of mechanical signals. ## Methods Chond
✦ LIBER ✦
Identification of known drugs that act as inhibitors of NF-κB signaling and their mechanism of action
✍ Scribed by Susanne C. Miller; Ruili Huang; Srilatha Sakamuru; Sunita J. Shukla; Matias S. Attene-Ramos; Paul Shinn; Danielle Van Leer; William Leister; Christopher P. Austin; Menghang Xia
- Book ID
- 113489102
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 462 KB
- Volume
- 79
- Category
- Article
- ISSN
- 0006-2952
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## Abstract The metastasis‐promoting protein S100A4 stimulates metastatic progression through both intracellular and extracellular functions. Extracellular activities of S100A4 include stimulation of angiogenesis, regulation of cell death and increased cell motility and invasion, but the exact mole