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Identification of Inhibitors of the Leishmania cdc2-Related Protein Kinase CRK3

✍ Scribed by Dr. Laura A. T. Cleghorn; Dr. Andrew Woodland; Iain T. Collie; Dr. Leah S. Torrie; Dr. Neil Norcross; Dr. Torsten Luksch; Dr. Chido Mpamhanga; Roderick G. Walker; Prof. Jeremy C. Mottram; Dr. Ruth Brenk; Prof. Julie A. Frearson; Prof. Ian H. Gilbert; Prof. Paul G. Wyatt

Book ID
102805548
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
680 KB
Volume
6
Category
Article
ISSN
1860-7179

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## Abstract __The NAD^+^‐dependent deacetylases, namely sirtuins, are involved in the regulation of a variety of biological processes such as gene silencing, DNA repair, longevity, metabolism, apoptosis, and development. An enzyme from the parasite__ Leishmania infantum __that belongs to this famil