Identification of in vivo phosphorylation sites of SET, a nuclear phosphoprotein encoded by the translocation breakpoint in acute undifferentiated leukemia

Characterization of the translocation br

Characterization of the translocation breakpoint sequences of two DEK-CAN fusion genes present in t(6;9) acute myeloid leukemia and a SET-CAN fusion gene found in a case of acute undifferentiated leukemia

✍ Marieke Von Lindern; Dimitri Breems; Sjozèf Van Baal; Henk Adriaansen; Gerard Gr 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 785 KB

The t(6;9) associated with a subtype of acute myeloid leukemia (AML) was shown t o generate a fusion between the 3' part of the CAN gene on chromosome 9 and the 5' part of the DEK gene on chromosome 6. The same part of the CAN gene appeared t o be involved in a case of acute undifferentiated leukemi