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Identification of IFRD1 as a modifier gene for cystic fibrosis lung disease

✍ Scribed by Gu, YuanYuan; Harley, Isaac T. W.; Henderson, Lindsay B.; Aronow, Bruce J.; Vietor, Ilja; Huber, Lukas A.; Harley, John B.; Kilpatrick, Jeffrey R.; Langefeld, Carl D.; Williams, Adrienne H.


Book ID
109898039
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
304 KB
Volume
458
Category
Article
ISSN
0028-0836

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## Abstract Genetic studies of lung disease in cystic fibrosis (CF) are hampered by the lack of a severity measure that accounts for chronic disease progression and mortality attrition. Further, combining analyses across studies requires common phenotypes that are robust to study design and patient