Identification of human transcriptional macromolecular associations using browser based in silico analysis in a giant correlation matrix

Identification of DPPA4 and other genes

Identification of DPPA4 and other genes as putative Sox2:Oct-3/4 target genes using a combination of in silico analysis and transcription-based assays

✍ Harini Chakravarthy; Brian Boer; Michelle Desler; Sunil Kumar Mallanna; Timothy 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 198 KB

## Abstract Sox2 and Oct‐3/4 function as master regulators during mammalian embryogenesis, where they are believed to regulate a critical gene regulatory network by cooperatively binding to DNA regulatory regions composed of adjacent HMG and POU motifs (HMG/POU cassettes). Previous studies have ide