Identification of human dopamine D1-like receptor agonist using a cell-based functional assay

Identification of soluble CD14 as an end

Identification of soluble CD14 as an endogenous agonist for Toll-like receptor 2 on human astrocytes by genome-scale functional screening of glial cell derived proteins

✍ Malika Bsibsi; Jeffrey J. Bajramovic; Eveline Van Duijvenvoorden; Carla Persoon; 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 620 KB

## Abstract Human astrocytes express a limited repertoire of Toll‐like receptor (TLR) family members including TLR1‐4, which are expressed on the cell surface. Also, TLR3 but not TLR4 activation on astrocytes induces expression of several factors involved in neuroprotection and down‐regulation of i