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Identification of Histidine-Rich Glycoprotein, a Potential Autoantigen, in Human and Rat Brain Preparations

✍ Scribed by CATRIN BALL-ROSEN; HAGIT PRIMAK-RUBINOVICZ; AMOS D. KORCZYN; NINGSHAN WANG; ADEL FARCHI; SARA SHAVIT; YEHUDA SHOENFELD; JOAB CHAPMAN

Book ID
111483475
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
115 KB
Volume
1109
Category
Article
ISSN
0890-6564

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The formation of histamine from its precursor histidine is catalyzed by histidine decarboxylase (HDC), a pyridoxal phosphate (PLP)-dependent decarboxylase. The knowledge of sequence similarities between various rodent HDCs permitted us to prepare a rat brain HDC cDNA probe. After reverse transcripti