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Identification of hepatic molecular mechanisms of action of alpha-tocopherol using global gene expression profile analysis in rats

✍ Scribed by Luca Barella; Patrick Y Muller; Manfred Schlachter; Willi Hunziker; Elisabeth Stöcklin; Volker Spitzer; Nina Meier; Sonia de Pascual-Teresa; Anne-Marie Minihane; Gerald Rimbach

Book ID
116270207
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
247 KB
Volume
1689
Category
Article
ISSN
0925-4439

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## Abstract To better understand the molecular basis of radiation‐induced osteosarcoma (OS), we performed global gene expression profiling of rat OS tumors induced by the bone‐seeking alpha emitter ^238^Pu, and the expression profiles were compared with those of normal osteoblasts (OB). The express