Molecular mobility of nifedipine–PVP and
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Yukio Aso; Sumie Yoshioka
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Article
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2006
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John Wiley and Sons
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English
⚖ 119 KB
Amorphous nifedipine-PVP and phenobarbital-PVP solid dispersions with various drug contents were prepared by melting and subsequent rapid cooling of mixtures of PVP and nifedipine, or phenobarbital. Chemical shifts and spin-lattice relaxation times (T(1)) of PVP, nifedipine, and phenobarbital carbon