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Identification of [(GS)2AsSe]− in rabbit bile by size-exclusion chromatography and simultaneous multielement-specific detection by inductively coupled plasma atomic emission spectroscopy

✍ Scribed by Jürgen Gailer; Sean Madden; Gavin A. Buttigieg; M. Bonner Denton; Husam S. Younis


Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
116 KB
Volume
16
Category
Article
ISSN
0268-2605

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✍ J. Gailer; G. A. Buttigieg; M. B. Denton 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 110 KB 👁 2 views

The seleno-bis (S-glutathionyl) arsinium ion, [(GS) 2 AsSe] -, which can be synthesized from arsenite, selenite and glutathione (GSH) at physiological pH, fundamentally links the mammalian metabolism of arsenite with that of selenite and is potentially involved in the chronic toxicity/carcinogenicit