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Identification of glucuronide metabolites of T-2 toxin and diacetoxyscirpenol in the bile of isolated perfused rat liver

✍ Scribed by Manfred Gareis; Ayman Hashem; Johann Bauer; Brigitte Gedek

Book ID
113206852
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
441 KB
Volume
84
Category
Article
ISSN
0041-008X

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The hepatobiliary disposition of rhodamine 123 (RH-123) and its glucuronidated (RH-Glu) and deacylated (RH-110) metabolites were studied in an isolated perfused rat liver (IPRL) model in the presence and absence of P-glycoprotein (P-gp) and Mrp2 inhibitors. A single dose (180 mg) of RH-123 was added