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Identification of genes whose expression is upregulated in lung adenocarcinoma cells in comparison with type II alveolar cells and bronchiolar epithelial cells in vivo

✍ Scribed by Kobayashi, Keiko; Nishioka, Michiho; Kohno, Takashi; Nakamoto, Masaki; Maeshima, Arafumi; Aoyagi, Kazuhiko; Sasaki, Hiroki; Takenoshita, Seiichi; Sugimura, Haruhiko; Yokota, Jun

Book ID: 110068510
Publisher: Nature Publishing Group
Year: 2004
Tongue: English
Weight: 288 KB
Volume: 23
Category: Article
ISSN: 0950-9232
DOI: 10.1038/sj.onc.1207433

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## Abstract Mutations in the tumor suppressor gene transforming growth factor β (TGFB) Type II receptor (__TGFBR2__) are frequently found in many cancers with microsatellite instability, but are less common in lung cancer. In the present study, we looked for mutations in __TGFBR2__ in nonsmall cell