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Identification of Functional Genetic Variants in Cyclooxygenase-2 and Their Association With Risk of Esophageal Cancer

✍ Scribed by Xuemei Zhang; Xiaoping Miao; Wen Tan; Baitang Ning; Zhihua Liu; Yuan Hong; Wenguang Song; Yongli Guo; Xinyu Zhang; Yan Shen; Boqin Qiang; Fred F. Kadlubar; Dongxin Lin


Book ID
119758578
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
323 KB
Volume
129
Category
Article
ISSN
0016-5085

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Cyclooxygenase-2 Gly587Arg variant is as
✍ Dan Zhao; Xuemei Zhang; Yongli Guo; Wen Tan; Dongxin Lin πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 130 KB

## Abstract Functional SNPs in the __COX‐2__ promoter region have been associated with susceptibility to esophageal squamous‐cell carcinoma (ESCC). In this study, we investigated SNPs in the __COX‐2__ coding region and their impact on risk of ESCC. The coding region of __COX‐2__ in DNAs from 30 Han