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Identification of Four Novel Human Genes Amplified and Overexpressed in Breast Carcinoma and Localized to the q11-q21.3 Region of Chromosome 17

✍ Scribed by C. Tomasetto; C. Régnier; C. Moog-Lutz; M.G. Mattei; M.P. Chenard; R. Lidereau; P. Basset; M.C. Rio

Book ID
115612727
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
698 KB
Volume
28
Category
Article
ISSN
0888-7543

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Genetic alterations of the tumour suppre
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✍ Tone I. Andersen; Astrid Gaustad; Anne-Lise Børresen; George W. Farrants; Jahn M 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 844 KB

## Abstract Fifty‐nine primary breast carcinomas and 11 metastases were examined to identify genetic alterations in the tumour suppressor gene regions 3p, 11p, 13q, 17p, and 17q. Loss of heterozygosity (LOH) was frequently observed on chromosome arms 17p (p144D6 lost in 75%, pYNZ22.1 in 55%, and __