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Identification of extracellular arsenical metabolites in the growth medium of the microorganisms apiotrichum humicola and scopulariopsis brevicaulis

✍ Scribed by William R. Cullen; Hao Li; Gary Hewitt; Kenneth J. Reimer; Nadia Zalunardo


Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
745 KB
Volume
8
Category
Article
ISSN
0268-2605

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✦ Synopsis


Abstract

The separation and identification of some of the arsenic species produced in cells present in the growth medium when the microorganisms Apiotrichum humicola (previously known as Candida humicola) and Scopulariopsis brevicaulis were grown in the presence of arsenicals were achieved by using hydride generation–gas chromatography–atomic absorption spectrometry methodology (HG GC AA). Arsenite, monomethylarsonate, dimethylarsinate and trimethylarsine oxide were detected following incubation with arsenate. With arsenite as a substrate, the metabolites were monomethylarsonate, dimethylarsinate and trimethylarsine oxide; monomethylarsonate afforded dimethylarsinate and trimethylarsine oxide, and dimethylarsinate afforded trimethylarsine oxide. Trimethylarsine was not detected when the arsenic concentration was 1 ppm.