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Identification of expressed sequence tags of genes expressed highly in the activated hepatic stellate cell

✍ Scribed by Sung Hee Lee; Keon-Sang Chae; Dong Hwan Sohn


Publisher
Springer
Year
2004
Tongue
English
Weight
629 KB
Volume
27
Category
Article
ISSN
0253-6269

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Hepatic stellate cell (HSC) activation is an essential event during liver fibrogenesis. Methionine adenosyltransferase (MAT) catalyzes biosynthesis of S-adenosylmethionine (SAMe), the principle methyl donor. SAMe metabolism generates two methylation inhibitors, methylthioadenosine (MTA) and S-adenos