๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Identification of essential residues in the potassium channel inhibitor ShK toxin: analysis of monosubstituted analogs

โœ Scribed by W.R. Kem; M.W. Pennington; V.M. Mahnir; M.E.I. Byrnes; I. Zaydenberg; I. Khaytin; D.S. Krafte; R. Hill; J. de Chastonay


Book ID
116074930
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
111 KB
Volume
34
Category
Article
ISSN
0041-0101

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Assignment of the three disulfide bonds
โœ Jan Pohl; Frantisek Hubalek; Michael E. Byrnes; Kurt R. Nielsen; Amina Woods; Mi ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› Springer Netherlands ๐ŸŒ English โš– 422 KB

ShK toxin, a 35-residue peptide isolated from the Caribbean sea anemone Stichodactyla helianthus, is a potent inhibitor of the Kv1.3 potassium channel in lymphocytes. The natural toxin contains three disulfide bonds. The disulfide pairings of the synthetic ShK toxin were elucidated as a prerequisite