✦ LIBER ✦

Identification of Dipeptidyl Nitriles as Potent and Selective Inhibitors of Cathepsin B through Structure-Based Drug Design

✍ Scribed by Greenspan, Paul D.; Clark, Kirk L.; Tommasi, Ruben A.; Cowen, Scott D.; McQuire, Leslie W.; Farley, David L.; van Duzer, John H.; Goldberg, Ronald L.; Zhou, Huanghai; Du, Zhengming; Fitt, John J.; Coppa, David E.; Fang, Zheng; Macchia, William; Zhu, Lijuan; Capparelli, Michael P.; Goldstein, Robert; Wigg, Andrew M.; Doughty, John R.; Bohacek, Regine S.; Knap, Ania K.

Book ID: 118129184
Publisher: American Chemical Society
Year: 2001
Tongue: English
Weight: 356 KB
Volume: 44
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm010206q

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Identification of Potent and Selective S

Identification of Potent and Selective Small-Molecule Inhibitors of Caspase-3 through the Use of Extended Tethering and Structure-Based Drug Design

✍ DeLano, Warren L.; Fahr, Bruce; Choong, Ingrid C.; Lew, Willard; Lee, Dennis; Ph 📂 Article 📅 2002 🏛 American Chemical Society 🌐 English ⚖ 651 KB

Structure-based design of selective and

Structure-based design of selective and potent G quadruplex-mediated telomerase inhibitors

✍ Read, M.; Harrison, R. J.; Romagnoli, B.; Tanious, F. A.; Gowan, S. H.; Reszka, 📂 Article 📅 2001 🏛 National Academy of Sciences 🌐 English ⚖ 300 KB

Structure Based Design of a Series of Po

Structure Based Design of a Series of Potent and Selective Non-Peptidic PTP-1B Inhibitors.

✍ Cheuk K. Lau; Christopher I. Bayly; et al. et al. 📂 Article 📅 2004 🏛 John Wiley and Sons ⚖ 95 KB 👁 2 views

BCX-1812 (RWJ-270201): Discovery of a No

BCX-1812 (RWJ-270201): Discovery of a Novel, Highly Potent, Orally Active, and Selective Influenza Neuraminidase Inhibitor through Structure-Based Drug Design

✍ Babu, Y. Sudhakar; Chand, Pooran; Bantia, Shanta; Kotian, Pravin; Dehghani, Ali; 📂 Article 📅 2000 🏛 American Chemical Society 🌐 English ⚖ 363 KB

ChemInform Abstract: Discovery of Potent

ChemInform Abstract: Discovery of Potent Inhibitors of Interleukin-2 Inducible T-Cell Kinase (ITK) Through Structure-Based Drug Design.

✍ Brian N. Cook; et al. et al. 📂 Article 📅 2009 🏛 John Wiley and Sons ⚖ 18 KB 👁 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v

Design and Synthesis of Tri-Ring P 3 Ben

Design and Synthesis of Tri-Ring P 3 Benzamide-Containing Aminonitriles as Potent, Selective, Orally Effective Inhibitors of Cathepsin K

✍ Palmer, James T.; Bryant, Clifford; Wang, Dan-Xiong; Davis, Dana E.; Setti, Edua 📂 Article 📅 2005 🏛 American Chemical Society 🌐 English ⚖ 392 KB