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Identification of D-galactose-(1 → 7)-3-deoxy-d-manno-2-octulo-pyranosonate as component of the inner core region of escherichia coli EH 100 lipopolysaccharide

✍ Scribed by O. Holst; E. Röhrscheidt-Andrzejewski; H.-P. Cordes; H. Brade


Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
297 KB
Volume
10
Category
Article
ISSN
0138-4988

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✦ Synopsis


The dissaccharide D-galactosyl-3-deoxy-D-ma~o-2-octulosonic acid (Gal-KDO) from lipopolysaccharides (LPS) of the inner core region of the rough mutant EHl00 of E. coli 0100 was isolated after mild acid hydrolysis of LPS by means of dialysis, ion-exchange chromatography, gelfiltration and high-voltage paper electrophoresis. By chemical analysis galactose and KDO were identified in a molar ratio of approximately 1 : 1. 13C-NMR and 'H-iWR studies, methylation analysis and GLC of the acetylated R-( -)-2-butyl-galactoside identified the structure