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Identification of cytokine-induced nuclear factor-kappaB target genes in ovarian and breast cancer cells

✍ Scribed by Valérie Deregowski; Sylvie Delhalle; Valérie Benoit; Vincent Bours; Marie-Paule Merville


Book ID
113993143
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
313 KB
Volume
64
Category
Article
ISSN
0006-2952

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## Abstract Transforming growth factor‐β1 (TGF‐β1) is a crucial molecule for stimulation of breast cancer invasion and formation of bone metastases. The molecular mechanisms of how TGF‐β1 mediates these effects have yet to be completely determined. We have found that activating transcription factor