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Identification of cyclophosphamide-DNA adducts in rat embryos exposed in vitro to 4-hydroperoxycyclophosphamide

✍ Scribed by Mirkes, Philip E.; Brown, Nigel A.; Kajbaf, Mahmud; Lamb, John H.; Farmer, Peter B.; Naylor, Stephen

Book ID
120556225
Publisher
American Chemical Society
Year
1992
Tongue
English
Weight
522 KB
Volume
5
Category
Article
ISSN
0893-228X

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## Abstract Intensive chemotherapy prior to harvesting autologous bone marrow may be advantageous for cancers that infiltrate the bone marrow. This approach, however, may deplete hemopoietic reserves or damage the hemopoietic microenvironment and thereby jeopardize posttransplant engraftment; in vi