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Identification of cis -acting DNA Elements Required for Expression of the Human Cardiac Troponin I Gene Promoter

✍ Scribed by Pankaj K Bhavsar; Kimberley A Dellow; Magdi H Yacoub; Nigel J Brand; Paul JR Barton


Book ID
115632952
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
523 KB
Volume
32
Category
Article
ISSN
0022-2828

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## Abstract Insulin gene expression in rat insulinoma (RIN) cells is extinct in RIN Γ— fibroblast hybrids and can reappear upon loss of DNA contributed by the fibroblast parent. (Besnard et al., Exp. Cell Res. __185:__101–108, 1989). In the present study, we looked for the role of 5′‐flanking sequen