## Abstract Chronic lymphocytic leukemia (CLL) is a clinically heterogeneous disease characterized by recurrent chromosomal aberrations of prognostic significance. We aimed to evaluate the potential of the multiplex ligationβdependent probe amplification (MLPA) assay to detect genomic alterations i
β¦ LIBER β¦
Identification of chromosomal abnormalities relevant to prognosis in chronic lymphocytic leukemia using multiplex ligation-dependent probe amplification
β Scribed by Marian Stevens-Kroef; Annet Simons; Hanneke Gorissen; Ton Feuth; Daniel Olde Weghuis; Arjan Buijs; Reinier Raymakers; Ad Geurts van Kessel
- Book ID
- 113513606
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 148 KB
- Volume
- 195
- Category
- Article
- ISSN
- 0165-4608
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## Communicated by John McVey The need to detect clinically significant segmental aneuploidies beyond the range of light microscopy demands the development of new cost-efficient, sensitive, and robust analytical techniques. Multiplex ligation-dependent probe amplification (MLPA) has already been sh