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Identification of Cell Surface Binding Sites for PC-Cell-Derived Growth Factor, PCDGF, (Epithelin/Granulin Precursor) on Epithelial Cells and Fibroblasts

โœ Scribed by Xianmin Xia; Ginette Serrero


Book ID
115581966
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
237 KB
Volume
245
Category
Article
ISSN
0006-291X

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โœ David Moscatelli ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 834 KB

Scatchard analysis of binding of 125I-basic fibroblast growth factor (FGF) to baby hamster kidney (BHK) cells revealed the presence of two binding sites: a high affinity site with KD of 20 pM and 80,000 sites per cell and a low affinity site with KD of about 2 nM and 600,000 sites per cell. The bind