Identification of PMLβRARA rearrangement
β
Jin-Yeong Han; Kyong-Eun Kim; Kyeong-Hee Kim; Joo-In Park; Jae-Seok Kim
π
Article
π
2007
π
Elsevier Science
π
English
β 581 KB
Acute promyelocytic leukemia (APL) is characterized by a reciprocal translocation, t(15;17) (q22;q12), resulting in fusion of the genes promyelocytic leukemia (PML) and retinoic acid receptor alpha (RARA). With conventional cytogenetic methods, these translocations are detected in about 70-90% of pa