Identification of CBS2 as a mitochondrial protein in Saccharomyces cerevisiae
✍ Scribed by Michaelis, Uwe ;Rödel, Gerhard
- Publisher
- Springer
- Year
- 1990
- Tongue
- English
- Weight
- 978 KB
- Volume
- 223
- Category
- Article
- ISSN
- 0026-8925
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2,6-diaminpurine (DAP) selectively inhibited mitochondrial protein synthesis in yeast cells with concomitant failure of cells to grow in non-fermentable (yeast extract, glycerol) medium. The selectivity was pronounced in all strains tested (15) nearly all of which were able to grow in yeast extract,
A conditional respiratory deficiency in yeast Saccharomyces cerevisiae is expressed as a result of a nuclear mutation in sup1 and sup2 genes (II and IV chromosomes, respectively), coding for a component of cytoplasmic ribosomes (Ter-Avanesyan et al. 1982). One such strain is studied here in detail.