Identification of benzofuro[2,3-b]quinoline derivatives as a new class of antituberculosis agents
✍ Scribed by Chiao-Li Yang; Chih-Hua Tseng; Yeh-Long Chen; Chih-Ming Lu; Chai-Lin Kao; Ming-Hsien Wu; Cherng-Chyi Tzeng
- Book ID
- 108116342
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- French
- Weight
- 227 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0223-5234
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## Abstract Treatment of 2‐hydroxy‐, 2‐mercapto‐, and 2‐ethoxycarbonylamino‐benzonitriles **12** with 2‐fluoro‐ or 2‐nitrophenacylbromides **13** under alkaline conditions provided the corresponding benzofuran, benzothiophene, and indole intermediates **10**, respectivelly. Nucleophilic cyclization
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