## Abstract ## Objective Fibroblasts play a crucial role in the development of systemic sclerosis (SSc), and antifibroblast antibodies (AFAs) capable of inducing a proinflammatory phenotype in fibroblasts have been detected in the sera of SSc patients. This study examined the prevalence of AFAs in
โฆ LIBER โฆ
Identification of autoantibodies to the I protein of the heterogeneous nuclear ribonucleoprotein complex in patients with systemic sclerosis
โ Scribed by Carlomaurizio Montecucco; Roberto Caporali; Fabio Cobianchi; Giuseppe Biamonti
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 872 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0004-3591
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Objective. To examine eosinophil activation, as reflected by evidence of eosinophil degranulation in the blood and affected tissues, in patients with diffuse and limited cutaneous forms of systemic sclerosis (SSc). Methods. Levels of the eosinophil-derived major basic protein (MBP), a marker of eos