## Abstract E6βassociated protein (E6AP) is a cellular ubiquitin protein ligase that mediates ubiquitylation and degradation of p53 in conjunction with the highβrisk human papillomavirus E6 proteins. However, the physiological functions of E6AP are poorly understood. To identify a novel biological
Identification of annexin 1 as a PU.1 target gene in leukemia cells
β Scribed by Yuko Iseki; Akemi Imoto; Toshio Okazaki; Hideo Harigae; Shinichiro Takahashi
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 535 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0145-2126
No coin nor oath required. For personal study only.
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## Abstract Annexin A1 (ANXA1) is a calciumβ and phospholipidβbinding protein involved in a broad range of cellular events. This study used molecular and microscopy approaches to explore the role of ANXA1 in mouse myoblast C2C12 cell differentiation. We report that ANXA1 expression increases during
## Abstract Chromosome rearrangements are found in many acute leukemias. As a result, genes at the breakpoints can be disrupted, forming fusion genes. One of the genes involved in several chromosome aberrations in hematological malignancies is __NUP98__ (11p15). As __NUP98__ is close to the 11p tel