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Identification of an external divalent cation-binding site in the pore of a cGMP-activated channel

✍ Scribed by Root, Michael J.; MacKinnon, Roderick


Book ID
122985985
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
699 KB
Volume
11
Category
Article
ISSN
0896-6273

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## Abstract The conductance of the gramicidin A single channels in glycerolmonooleate membranes is strongly reduced in the presence of Mn^2+^ cations. The nmr experiments were performed for N‐terminal to N‐terminal gramicidin A dimer formed by two right‐handed single‐stranded helixes incorporated i