𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Identification of an antigen associated with malignant melanoma

✍ Scribed by D. Viza; J. Phillips

Book ID
102276452
Publisher
John Wiley and Sons
Year
1975
Tongue
French
Weight
393 KB
Volume
16
Category
Article
ISSN
0020-7136

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✦ Synopsis

Abstract

Xeno‐antisera, prepared by immunization with soluble membrane material obtained from melanoma tumours and partially purified by column chromatography, were found to detect an antigenic specificity common to some tumour extracts and sera of melanoma patients. The presence of this antigen in patients' sera allows speculation for its possible use for early diagnosis of metastases and its role in the blocking of the immunological defences of the melanoma patients. Preparation of monospecific antisera by immunization with insoluble serum‐antigen/antibody complexes has been successfully undertaken.

πŸ“œ SIMILAR VOLUMES

Membrane associated antigens of human ma
Membrane associated antigens of human malignant melanoma. III. Specificity of human sera reacting with cultured melanoma cells
✍ Edelgard Seibert; C. G. R. Sor Happle; E. Macher πŸ“‚ Article πŸ“… 1977 πŸ› John Wiley and Sons 🌐 French βš– 613 KB

## Abstract Sera from melanoma patients, healthy donors, pregnant women and patients with types of tumors other than melanoma were tested on various melanoma lines as well as on a cultured brain tumor and adult skin fibroblasts, using a microimmune adherence test. Positive reactions against all cel