Identification of an amino acid substitution in thebenA, ?-tubulin gene ofAspergillus nidulans that confers thiabendazole resistance and benomyl supersensitivity

Amino acid alterations in thebenA (β-tub

Amino acid alterations in thebenA (β-tubulin) gene ofAspergillus nidulans that confer benomyl resistance

✍ Jung, M. Katherine ;Wilder, Isaac B. ;Oakley, Berl R. 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 516 KB

## Abstract We report the cloning and sequencing of 18 mutant alleles of the __benA__, β‐tubulin gene of __Aspergillus nidulans__ that confer resistance to the benzimidazole antifungal, antimicrotubule compounds benomyl, carbendazim, nocodazole, and thia‐bendazole. In 12 cases, amino acid 6 was cha