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Identification of AFAP1L1 as a prognostic marker for spindle cell sarcomas

โœ Scribed by Furu, M; Kajita, Y; Nagayama, S; Ishibe, T; Shima, Y; Nishijo, K; Uejima, D; Takahashi, R; Aoyama, T; Nakayama, T

Book ID
109972793
Publisher
Nature Publishing Group
Year
2011
Tongue
English
Weight
801 KB
Volume
30
Category
Article
ISSN
0950-9232

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## Abstract Aberrant methylation of several tumor suppressor genes often occurs during the pathogenesis of lung cancer. RASSF1A is one of the tumor suppressor genes, and it is frequently inactivated by hypermethylation of its promoter region in a variety of human cancers, including lung cancer. It