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Identification of aberrant promoter hypomethylation of HOXA10 in ovarian cancer

✍ Scribed by Wenjun Cheng; Yi Jiang; Cuixia Liu; Ouxi Shen; Weiwei Tang; Xinru Wang

Book ID
106124239
Publisher
Springer-Verlag
Year
2010
Tongue
English
Weight
379 KB
Volume
136
Category
Article
ISSN
1432-1335

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## Abstract Trefoil factors, mucin‐associated peptides, are overexpressed in prostate cancer (PC). We hypothesized that promoter methylation contributes to the regulation of trefoil factors (TFF1, TFF2 and TFF3) in human prostate cells. Here we show hypomethylation of promoter regions of TFF1 and T