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Identification of a Third Region of Cell-Specific Alternative Splicing in Human Fibronectin mRNA

โœ Scribed by Alejandro Gutman and Alberto R. Kornblihtt

Book ID
123634792
Publisher
National Academy of Sciences
Year
1987
Tongue
English
Weight
795 KB
Volume
84
Category
Article
ISSN
0027-8424

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## Abstract The fibronectin (FN) gene encodes multiple mRNAs through the process of alternative splicing, and production of certain isoforms is characteristic of a given cell type. Chondrocytes produce FNs that completely lack alternative exon EIIIA, and loss of inclusion of the exon is tightly lin