Small supernumerary marker chromosomes are seldom found in prenatal diagnosis and the majority of them are difficult to identify. The only possibility to give a more precise prognosis is by establishing its origin. FISH is the best technique to identify the chromosomal origin, but in the majority of
โฆ LIBER โฆ
Identification of a supernumerary marker derived from chromosome 17 using FISH
โ Scribed by Rosenberg, Carla ;Borovik, Cleide L. ;Canonaco, Rosane S. ;Sichero, Laura C. ;Queiroz, Ana Paula S. ;Vianna-Morgante, Angela M.
- Book ID
- 101445634
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 275 KB
- Volume
- 59
- Category
- Article
- ISSN
- 0148-7299
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We describe a 38-year-old adult who has a supernumerary marker chromosome in 40% of metaphase cells which was identified by reverse in situ hybridization with a DNA probe made by microdissection to be derived from chromosome 17. The breakpoints are estimated by G-banding and fluorescence in situ hyb
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