Identification of 8 new mutations in Bra
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Ana B.A. Perez; Lygia V. Pereira; Decio Brunoni; Mayana Zatz; Maria Rita Passos-
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Article
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1999
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John Wiley and Sons
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English
⚖ 25 KB
👁 2 views
Marfan Syndrome (MFS) is a connective tissue disease caused by mutations in the fibrillin-1 (FBN1) gene. Screening for mutations in all the 65 exons of the FBN1 gene in 34 unrelated patients were performed to compare the efficiency of SSCP versus Heteroduplex analysis and to verify if the spectrum o