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Identification of a specific reprogramming-associated epigenetic signature in human induced pluripotent stem cells

✍ Scribed by Ruiz, S.; Diep, D.; Gore, A.; Panopoulos, A. D.; Montserrat, N.; Plongthongkum, N.; Kumar, S.; Fung, H.-L.; Giorgetti, A.; Bilic, J.; Batchelder, E. M.; Zaehres, H.; Kan, N. G.; Scholer, H. R.; Mercola, M.; Zhang, K.; Izpisua Belmonte, J. C.

Book ID
115469364
Publisher
National Academy of Sciences
Year
2012
Tongue
English
Weight
969 KB
Volume
109
Category
Article
ISSN
0027-8424

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## Abstract Induced pluripotent stem (iPS) cells derived from terminally differentiated human fibroblasts are reprogrammed to possess stem cell like properties. However, the extent to which iPS cells exhibit unique properties of the human embryonic stem (hES) cell cycle remains to be established. h