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Identification of a rearranged degradation product from carbamazepine-10,11-epoxide

✍ Scribed by K. M. Baker; A. Frigerio; P. L. Morselli; G. Pifferi

Publisher
John Wiley and Sons
Year
1973
Tongue
English
Weight
188 KB
Volume
62
Category
Article
ISSN
0022-3549

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A highly-sensitive microcolumn HPLC method for the simultaneous determination of carbamazepine and carbamazepine-l0,ll-epoxide in human serum and saliva is described. The method was successfully employed for the study of pharmacokinetics of carbamazepine in humans. After oral administration of 100 a