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Identification of a rare polymorphism in the human TP53 promoter

✍ Scribed by Claire L Attwooll; Gail McGown; Mary Thorncroft; Fiona J Stewart; Jillian M Birch; Jennifer M Varley

Book ID: 114135304
Publisher: Elsevier Science
Year: 2002
Tongue: English
Weight: 337 KB
Volume: 135
Category: Article
ISSN: 0165-4608
DOI: 10.1016/s0165-4608(01)00649-5

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## Abstract The __TP53__ tumor suppressor gene regulates a number of genes that are involved in cell‐cycle inhibition, apoptosis, and maintaining genetic stability. Recently, two genes that have a role in immunosurveillance were identified as downstream targets of TP53. These genes, __TAP1__ and __