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Identification of a protein component of the Ca2+-dependent K+ channel by affinity labelling with apamin

✍ Scribed by Michel Hugues; Heidy Schmid; Michel Lazdunski


Book ID
117056224
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
694 KB
Volume
107
Category
Article
ISSN
0006-291X

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Solution structure of TsKapa, a charybdo
✍ E. Blanc; C. Lecomte; J. Van Rietschoten; J.M. Sabatier; H. Darbon πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 802 KB

TsKapa (TsK), purified from the Buthidae Tityus serrulatus is a very high potent ligand for small-conductance apaminsensitive calcium-activated potassium channels (SK). It is able to efficiently compete with apamin for binding on this channel (K 0.5 ‫؍‬ 0.3 nM) [Legros, C. et al., FEBS Lett. 390:81-