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Identification of a promiscuous HLA DR–restricted T-cell epitope derived from the inhibitor of apoptosis protein survivin

✍ Scribed by Matthias Piesche; York Hildebrandt; Florian Zettl; Björn Chapuy; Marc Schmitz; Gerald Wulf; Lorenz Trümper; Roland Schroers

Book ID
116531479
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
365 KB
Volume
68
Category
Article
ISSN
0198-8859

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✍ Frank Neumann; Claudia Wagner; Stefan Stevanovic; Boris Kubuschok; Claudia Schor 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 French ⚖ 129 KB

## Abstract The __SSX2__ gene encodes the tumor‐specific antigen HOM‐MEL‐40/SSX2 expressed in a broad spectrum of tumors of different origin, against which humoral and CD8^+^ T‐cell‐mediated MHC‐I‐restricted responses have been demonstrated. Searching for promiscuous MHC‐II‐restricted peptides that