Identification of a Potent Sodium Hydrogen Exchanger Isoform 1 (NHE1) Inhibitor with a Suitable Profile for Chronic Dosing and Demonstrated Cardioprotective Effects in a Preclinical Model of Myocardial Infarction in the Rat

✍ Scribed by Huber, John D.; Bentzien, Jörg; Boyer, Stephen J.; Burke, Jennifer; De Lombaert, Stéphane; Eickmeier, Christian; Guo, Xin; Haist, James V.; Hickey, Eugene R.; Kaplita, Paul; Karmazyn, Morris; Kemper, Raymond; Kennedy, Charles A.; Kirrane, Thomas; Madwed, Jeffrey B.; Mainolfi, Elizabeth; Nagaraja, Nelamangara; Soleymanzadeh, Fariba; Swinamer, Alan; Eldrup, Anne B.

• Book ID: 120071634
• Publisher: American Chemical Society
• Year: 2012
• Tongue: English
• Weight: 765 KB
• Volume: 55
• Category: Article
• ISSN: 0022-2623
• DOI: 10.1021/jm300601d