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Identification of a nuclear protein that promotes NF-κB activation

✍ Scribed by Danying Chen; Zhiqin Li; Qian Yang; Jingbo Zhang; Zhonghe Zhai; Hong-Bing Shu

Book ID
116287139
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
200 KB
Volume
310
Category
Article
ISSN
0006-291X

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## Abstract Inhibitor of κB kinase (IKK) gamma (IKKγ), also referred to as nuclear factor κB (NF‐κB) essential modulator (NEMO), is an important regulatory component of the IKK complex. The IKK complex is a signalosome that catalyzes the inducible phosphorylation of IκB proteins, which is a key ste