TGFBR1 and TGFBR2 mutations in patients
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Krishna Kumar Singh; Kathrin Rommel; Anjali Mishra; Matthias Karck; Axel Haveric
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Article
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2006
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John Wiley and Sons
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English
⚖ 192 KB
👁 1 views
Marfan syndrome (MFS) is an autosomal dominant connective tissue disorder characterized by manifestations in the cardiovascular, skeletal, ocular, and other organ systems. MFS type1 (MFS1) is caused by mutations in the gene encoding fibrillin (FBN1). Recently, the transforming growth factor-beta rec