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Identification of a novel sugar, 4-amino-4,6-dideoxy-2-O-methylmannose in the lipopolysaccharide of Vibrio cholerae O1 serotype Ogawa

✍ Scribed by Teruyo Ito; Tsunehiko Higuchi; Masaaki Hirobe; Keiichi Hiramatsu; Takeshi Yokota

Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
874 KB
Volume
256
Category
Article
ISSN
0008-6215

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✦ Synopsis

A novel sugar in the lipopolysaccharide of Vibrio cholerae O1 serotype Ogawa has been identified. The sugar was liberated from the lipopolysaccharide when hydrolyzed in 10 M HCl at 90 degrees C for 15 min. The sugar was purified and identified as 4-amino-4,6-dideoxy-2-O-methylmannose (2-O-methylperosamine). Since it was found only in the lipopolysaccharide of Vibrio cholerae O1 serotype Ogawa, it seems that the sugar is one of the specific constituents determining Ogawa serotype specificity.

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